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Consult a healthcare professional before use if pregnant, breastfeeding, or taking medications. Do not exceed the recommended daily dose.
Biologically active folate bypassing MTHFR enzyme conversion. Critical for methylation.
The biologically active form of folate directly donating methyl groups without requiring MTHFR enzyme. Bypasses MTHFR polymorphisms (C677T, A1298C) that reduce folate activation in up to 40 percent of the population.
| Population | Safety rating | Max safe dose |
|---|---|---|
| General | Likely safe | — |
| Pregnancy | Likely safe | — |
| Elderly | Likely safe | — |
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)