Phenylketonuria: does not contain phenylalanine (unlike aspartame). Animal studies at supraphysiological doses suggested possible gut microbiome effects — not confirmed in humans at food use levels. Generally considered safe. Pregnant women: prefer to minimise non-nutritive sweetener use.
Non-nutritive synthetic sweetener 200x sweeter than sucrose. E950. Heat-stable. Widely used in combination with sucralose. FDA-approved. Safety studied for decades.
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
| Population | Safety rating | Max safe dose |
|---|---|---|
| General | Possibly safe | — |
| Pregnancy | Possibly safe | — |
| Elderly | Possibly safe | — |
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)