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Carotenodermia at very high doses (harmless skin yellowing). Smokers: beta-carotene supplements increase lung cancer risk — same caution applies.
Alpha-carotene is a provitamin A carotenoid found in carrots and pumpkin. Converted to Vitamin A in the body. Has independent antioxidant and anti-cancer properties.
Concentrated in lipid-rich tissues providing singlet oxygen quenching and free radical scavenging within lipid membranes. In humans, serve as provitamin A precursors or direct modulators of gene expression via PPAR and RXR receptors.
| Population | Safety rating | Max safe dose |
|---|---|---|
| General | Likely safe | — |
| Pregnancy | Likely safe | — |
| Elderly | Likely safe | — |
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)