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Limited long-term human data. Generally well tolerated.
Alpha-ketoglutarate (AKG) is a key intermediate in the Krebs cycle. Used for anti-ageing, muscle recovery, wound healing, and longevity research.
Serves as building block for protein synthesis or direct precursor for neurotransmitters, hormones, and enzymatic cofactors. Participates in nitrogen metabolism, energy production, and cellular signalling pathways relevant to studied health outcomes.
| Population | Safety rating | Max safe dose |
|---|---|---|
| General | Possibly safe | — |
| Pregnancy | Possibly safe | — |
| Elderly | Possibly safe | — |
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)