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Must be taken with food to avoid GI upset (nausea, cramping common on empty stomach). Avoid in pregnancy — safety data absent.
Ayurvedic nootropic herb with emerging evidence for memory and cognitive enhancement. Trials require 8-12 weeks minimum for cognitive effects. Bacosides A and B are primary active compounds.
Bacosides enhance synaptic transmission by increasing protein kinase activity in hippocampus. Modulate acetylcholine, serotonin, and dopamine signalling. Antioxidant via superoxide dismutase upregulation.
| Population | Safety rating | Max safe dose |
|---|---|---|
| General | Possibly safe | — |
| Pregnancy | Possibly safe | — |
| Elderly | Possibly safe | — |
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)