IARC Group 2B (possibly carcinogenic to humans). California Proposition 65 carcinogen. Potential endocrine disruption — thyroid and oestrogenic effects in animal studies. Avoid in high chronic exposure. Japan has restricted BHA in some food applications. Prefer natural antioxidant alternatives where possible.
Synthetic phenolic antioxidant used as a preservative in food, cosmetics, and pharmaceuticals. BHA (E320) is listed as a reasonably anticipated human carcinogen (NTP) based on animal studies. Endocrine-disrupting potential. California Proposition 65 listed. IARC Group 2B.
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
| Population | Safety rating | Max safe dose |
|---|---|---|
| General | Possibly unsafe | — |
| Pregnancy | Possibly unsafe | — |
| Elderly | Possibly unsafe | — |
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)