class="blog wp-embed-responsive wp-theme-foxiz wp-child-theme-foxiz-child supp-body td-standard-pack personalized-all menu-ani-1 hover-ani-1 btn-ani-1 btn-transform-1 is-rm-1 lmeta-dot loader-1 dark-sw-1 mtax-1 is-hd-5 is-backtop none-m-backtop is-mstick is-smart-sticky"
GI irritation: enteric coated forms preferred. Warfarin interaction. Surgery: discontinue.
Capsaicin oral supplementation for pain management via TRPV1 receptor modulation and substance P depletion.
Inhibits key inflammatory enzymes (COX-1/2, 5-LOX) or transcription factors (NF-kB, AP-1) reducing prostaglandin, leukotriene, and cytokine production. Some activate PPAR-gamma nuclear receptor mediating anti-inflammatory gene transcription.
| Population | Safety rating | Max safe dose |
|---|---|---|
| General | Possibly safe | — |
| Pregnancy | Possibly safe | — |
| Elderly | Possibly safe | — |
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)