class="wp-theme-Newspaper supp-body td-standard-pack global-block-template-1 tdc-header-template tdc-footer-template td-animation-stack-type0 td-full-layout"
← All ingredients
SAFE

Citicoline (CDP-choline)

Cytidine 5′-diphosphocholine

Possibly Safe 6 PubMed studies PubChem 13804 ↗

Contraindications & warnings

Very safe profile in clinical trials. Cholinergic: headache, nausea at high doses. Drug interactions: levodopa (additive benefit but monitor). Generally very safe at 250-1000mg/day.

About

Nucleoside derivative providing both cytidine and choline. Phospholipid precursor for brain membrane synthesis. Used for stroke recovery, traumatic brain injury, and cognitive enhancement. Approved pharmaceutical in several countries (Ceraxon, Somazina).

Mechanism of action

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

Safety by population

Population Safety rating Max safe dose
General Possibly safe
Pregnancy Possibly safe
Elderly Possibly safe

Effectiveness

No peer-reviewed clinical trial data found for this ingredient.

Medical disclaimer: This information is for educational purposes only. It does not constitute medical advice. Always consult a qualified healthcare professional before taking any supplement or changing your medication.

Data by supplement.ge — Public Health Institute of Georgia (PHIG)