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SAFE

Dihydrolipoic acid

Dihydrolipoic acid (DHLA) — reduced form of ALA

Possibly Safe 1 PubMed studies PubChem 421 ↗

Contraindications & warnings

See alpha-lipoic acid. As direct supplement limited data. Antioxidant properties similar. Hypoglycaemia risk.

About

Reduced form of alpha-lipoic acid. Endogenously generated from ALA by lipoamide dehydrogenase. More potent antioxidant than oxidised ALA. Generally taken as ALA which converts to DHLA in vivo.

Mechanism of action

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

Safety by population

Population Safety rating Max safe dose
General Possibly safe
Pregnancy Possibly safe
Elderly Possibly safe

Effectiveness

No peer-reviewed clinical trial data found for this ingredient.

Medical disclaimer: This information is for educational purposes only. It does not constitute medical advice. Always consult a qualified healthcare professional before taking any supplement or changing your medication.

Data by supplement.ge — Public Health Institute of Georgia (PHIG)