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← All ingredients
SAFE

Dihydromyricetin

DHM (Hovenia dulcis extract)

Possibly Safe 2 PubMed studies PubChem 161557 ↗

Contraindications & warnings

GABAergic medication interaction. Pregnancy: insufficient data. Generally well tolerated.

About

GABA-A modulator from Japanese raisin tree. Used for alcohol metabolism, liver protection, and anxiety.

Mechanism of action

Enhances cognitive function via cholinergic system activation, cerebrovascular blood flow improvement, or neuroplasticity enhancement via BDNF/NGF upregulation. Neuroprotective mechanisms include antioxidant activity and reduction of excitotoxic glutamate signalling.

Safety by population

Population Safety rating Max safe dose
General Possibly safe No established UL
GABAergic medication interaction. Generally well tolerated.

Effectiveness

No peer-reviewed clinical trial data found for this ingredient.

Medical disclaimer: This information is for educational purposes only. It does not constitute medical advice. Always consult a qualified healthcare professional before taking any supplement or changing your medication.

Data by supplement.ge — Public Health Institute of Georgia (PHIG)