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Oestrogen-sensitive conditions: consult physician. GI effects. Headache. Drug interaction via CYP enzymes.
DIM is a stable metabolite of I3C that modulates oestrogen metabolism towards protective 2-OHE1 pathway. Used for hormone balance and cancer prevention.
Provides targeted nutritional substrate or pharmacological activity for specific biochemical pathways not adequately supported by standard dietary intake. Mechanism involves enzyme cofactor provision, receptor modulation, or membrane structural modification.
| Population | Safety rating | Max safe dose |
|---|---|---|
| General | Possibly safe | — |
| Pregnancy | Possibly safe | — |
| Elderly | Possibly safe | — |
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)