Generally well tolerated. Limited robust clinical evidence. GRAS status uncertain in some jurisdictions. Very limited long-term safety data. May cause mild stimulant effect.
Methyl donor amino acid derivative. Precursor to glycine and methyl groups. Used for energy, immune support, and autism spectrum disorder (limited evidence). Pangamic acid ("Vitamin B15") component.
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
| Population | Safety rating | Max safe dose |
|---|---|---|
| General | Possibly safe | — |
| Pregnancy | Possibly safe | — |
| Elderly | Possibly safe | — |
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)