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SAFE

Diosmin

Diosmin (citrus flavone glycoside)

Likely Safe 56 PubMed studies PubChem 5281613 ↗

Contraindications & warnings

Generally very safe. Part of Daflon formulation. Pregnancy: limited data.

About

Diosmin is a flavonoid from citrus with venotonic and vasoprotective effects. Used for chronic venous disease and haemorrhoids.

Mechanism of action

Modulates cardiovascular function via eNOS activation for vasodilation, inhibition of platelet aggregation, and venotonic effects strengthening venous wall integrity. Antioxidant effects protect LDL from oxidative modification reducing atherosclerosis progression.

Safety by population

Population Safety rating Max safe dose
General Likely safe
Pregnancy Likely safe
Elderly Likely safe

Effectiveness

No peer-reviewed clinical trial data found for this ingredient.

Medical disclaimer: This information is for educational purposes only. It does not constitute medical advice. Always consult a qualified healthcare professional before taking any supplement or changing your medication.

Data by supplement.ge — Public Health Institute of Georgia (PHIG)