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SAFE

Epigallocatechin

Epigallocatechin (EGC)

Likely Safe 239 PubMed studies PubChem 72277 ↗

Contraindications & warnings

Very safe. Different from EGCG. Combined in green tea extracts.

About

EGC is a catechin from green tea. Along with EGCG, provides the majority of green tea's health benefits.

Mechanism of action

Acts as direct free radical scavenger and indirect antioxidant via Nrf2/ARE pathway activation. Modulates inflammatory signalling via NF-kB and AP-1 inhibition. Interacts with kinase pathways (MAPK, PI3K/Akt, mTOR) and epigenetic regulators relevant to anti-ageing and disease prevention.

Safety by population

Population Safety rating Max safe dose
General Likely safe
Pregnancy Likely safe
Elderly Likely safe

Effectiveness

No peer-reviewed clinical trial data found for this ingredient.

Medical disclaimer: This information is for educational purposes only. It does not constitute medical advice. Always consult a qualified healthcare professional before taking any supplement or changing your medication.

Data by supplement.ge — Public Health Institute of Georgia (PHIG)