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SAFE

Gamma-Aminobutyric Acid

GABA (gamma-aminobutyric acid)

Possibly Safe 557 PubMed studies PubChem 119 ↗

Contraindications & warnings

CNS depressant interaction. Pregnancy: insufficient data. Generally well tolerated at supplement doses.

About

Exogenous GABA supplementation has anxiolytic and sleep-promoting effects. Debate exists on whether oral GABA crosses the blood-brain barrier.

Mechanism of action

Serves as building block for protein synthesis or direct precursor for neurotransmitters, hormones, and enzymatic cofactors. Participates in nitrogen metabolism, energy production, and cellular signalling pathways relevant to studied health outcomes.

Safety by population

Population Safety rating Max safe dose
General Possibly safe
Pregnancy Possibly safe
Elderly Possibly safe

Effectiveness

No peer-reviewed clinical trial data found for this ingredient.

Medical disclaimer: This information is for educational purposes only. It does not constitute medical advice. Always consult a qualified healthcare professional before taking any supplement or changing your medication.

Data by supplement.ge — Public Health Institute of Georgia (PHIG)