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Mild antiplatelet effects at doses above 4g/day. Caution in patients on anticoagulants. Pregnancy: effective for nausea but avoid doses above 1g/day — evidence for higher doses limited.
Culinary spice with well-established antiemetic properties. Effective for nausea and vomiting of pregnancy, chemotherapy-induced nausea, and post-operative nausea. GRAS status in USA.
Gingerols and shogaols inhibit 5-HT3 receptors (mechanism of antiemetic effect). Inhibit COX-1, COX-2 and prostaglandin synthesis. Mild antiplatelet activity via thromboxane inhibition.
No peer-reviewed clinical trial data found for this ingredient.
Data by supplement.ge — Public Health Institute of Georgia (PHIG)